From the Blog

Zenpep, the New Enzyme on the Block

Since I’ve been battling gaining weight for so long, I mentioned my desire to fatten up every time I go to clinic. I’ve had some really rough bouts with intestinal blockages this year. I had two in just 3 months, and one put me in the hospital overnight after spending all night and all day in the ER because regular medical staff can’t wrap their heads around the fact that I had two feet of my small intestine removed at birth. I did some calculations and came up with figures that call that 25-40% of my small intestine. There is scar tissue and some bottleneck in there that binds from time to time.

After my last episode, I was messed up for weeks. I was in pain for over a week and my normal body rhythm was all out of whack. There was bloating, gas, discomfort, chronic bathroom breaks, etc. One evening with family over, I went to the bathroom 10 times after dinner. Something had to change! Eventually, things returned to normal, but I was still deadlocked at 108-111lbs.

I went to clinic on February 19th and mentioned to my coordinator that things were still “not right” and told her my 3 main complaints were still bothering me. She said that a new enzyme just got approved and she had a sample bottle available for me. It’s called Zenpep. If I liked its results, my aerosol supplier ships the enzymes, too.

I went home and tried it that afternoon. That evening, no excessive bloating or bathroom trips. The next day brought the same good news, plus some added bonus of gaining 1.2lbs. The next time I weighed myself, I’d gained 2.5lbs. Things were on the move in the direction I wanted. During the time between running out of the samples and my new shipment arriving today, my old enzymes were their usual mess, shall we say. Today, I’m all better again.

Enzymes can really make a difference in your life.

Here is my theory on why Zenpep is working so much better for me than Ultrase MT20 and Creon MT20 have been: the amounts of enzymes within each capsule is vastly different. For example:

Ultrase MT 20:
lipase 20,000 USP units
amylase 65,000 USP units
protease 65,000 USP units
Zenpep:
lipase 20,000 USP units
amylase 109,000 USP units
protease 68,000 USP units

You’ll notice a nearly two-fold increase in the amount of amylase in Zenpep. Now, I haven’t done any research on why they use this formulation, but here is what my research about those enzymes came up with:

amylase – Amylase is an enzyme which helps digest glycogen and starch. It is produced mainly in the pancreas and salivary glands.

lipase – Lipase; an enzyme secreted in the digestive tract that catalyzes the breakdown of fats into individual fatty acids that can be absorbed into the bloodstream.

protease – Enzymes acting on peptide bonds. EC 3.4.-

Given the nature of much of the nutrition we eat trying to gain massive amounts of calories (complex carbohydrates), it stands to reason in my head, dangerously educated by 2 semesters of chemistry and a growing understanding of my body chemistry with the advent of diabetes risk, that my diet requires higher concentrations of amylase to process those complex carbs.

I would highly recommend asking your doctor or clinic coordinator about Zenpep. They even offer up to a $50 rebate on your co-pays through December, so long as you have private insurance, not gov’t insurance. I’ll be getting these for free!

Comments

  1. Creon 24,000 USP formerly Creon 20 has:

    lipase 24,000 USP units
    amylase 120,000 USP units
    protease 76,000 USP units

    So actually Creon actually exceeds Zenpep in all categories.

    Also the company also has a benefits program, with a months supply of Creon you get free vitamins (Source cf or Vitamax), and a months supply of high calorie drink.

  2. Creon 24,000 USP formerly Creon 20 has:

    lipase 24,000 USP units
    amylase 120,000 USP units
    protease 76,000 USP units

    So actually Creon actually exceeds Zenpep in all categories.

    Also the company also has a benefits program, with a months supply of Creon you get free vitamins (Source cf or Vitamax), and a months supply of high calorie drink.

  3. Creon 24 is not an apples to apples comparison. Check the units on Creon 20 – lipase is guaranteed to be 20,000 b/c that's what the 20 and 24 mean, so it would make sense that the other enzymes would be in higher quantities in a 24, too.

  4. chillcutt says

    They no longer make Creon 20 and Creon 24,000 is the highest form they make. i was comparing the highest from both companies. Creon Doesn't make a formalization exactly like zenpep. I am impartial to creon because around 6 years ago i was on ultrase and was changed to creon and went from around 125 to 140+ in a matter of months. So different enzymes work for different people. I am really excited about the drug Liprotamase could cut down on number of enzymes that have to be taken and it is also porcine-free, where all others contain them.

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